The DNA and Natural Algorithms Group:

Movie of water-in-oil droplets containing a 'genelet' oscillator

Time-lapse fluorescence microscopy movie of oscillating droplets, showing that smaller droplets have larger variability in the frequency of their oscillations. By the end of the roughly 17 hour duration of the experiment, the chemical energy sources driving the oscillations have been depleted, and the reaction settles down. (Motion of the droplets midway through the movie are due to spurious fluid flow in the microscopy set-up, and are not relevant to the phenomena being studied.) The 'sustained' tuning of the oscillator is used. This movie was taken by our collaborators at the Technical University of Munich (TUM).

For more information on this work, please see "Diversity in the dynamical behaviour of a compartmentalized programmable biochemical oscillator", Maximilian Weitz, Jongmin Kim, Korbinian Kapsner, Erik Winfree, Elisa Franco and Friedrich C. Simmel, Nature Chemistry, February 16, 2014 (doi:10.1038/nchem.18694)

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